What is high mileage? I've had 2 V8's past 100,000 miles with no issues, I currently have 2 V4 motorbikes, one 4 years old one 7 years old, both with over 90,000 miles. Only issues with the bikes is tyres and a new clutch on each.
I've had 3 suzuki cappuccino's, one I sold with 104,000 on it and then the new owner used it as an every day commute and soon got it up over 150,000 miles. This is a 3 cylinder 657cc turbo car. Only problem with the suzi's was rust and clutches.