Here's a route taking in all the road passes in the Lakes. It includes the following:
Wrynose Pass - east/west
Dunnerdale
Ulpha Fell
Wasdale
Hardknott Pass
Wrynose Pass - west/east
Greater Langdale
Red Bank
Thirlmere
Derwent Water & Borrowdale - north/south
Honister Pass - east/west
Buttermere
Crummock Water
Whinlatter Pass
Newlands Pass
Honister Pass - west/east
Derwent Water & Borrowdale - south/north
Ullswater
Glenridding
Kirkstone Pass & The Struggle
Wrynose and Honister Pass are driven both ways. Although the detour into Wasdale is not a logical part of the route, it's a worthwhile addition to it.
Total Distance: 140 miles
Total Time: Depends when done - best early morning or evening. Slow and tedious during the day in high season.
Scenically the route includes the best of the Lake District.
The road to the south of Thirlmere now looks like this:
