When we went, we based out tour on the Scenic Car Tours route. As there were only going to be two cars, they weren't able to offer the trip bespoke to us. They did however get us a good discount on the ferries.
We started in the North so not quite what you are looking for but may be helpful.
Our route was:
Belfast - Hilton Templepatrick, Paradise Walk, Castle Upton Estate, Templepatrick BT39 0DD 028 9508 2000
Causeway - Magherabuoy House Hotel 41 Magheraboy Road, Portrush, Co. Antrim. BT56 8NX 028 70823507
Donegal - Sandhouse, Rossnowlagh Beach, Rossnowlagh, Co. Donegal. F94 X56F +353 71 98 51777
Westport - Westport Country Lodge Hotel Aughagower, Co. Mayo, Ireland, F28 P642 +353 98 56030
Galway - Ardilaun Hotel, Taylors Hill, Galway, H91 H29F, Ireland +353 91 521433
Killarney - Dromhall Hotel, Muckross Road, Killarney, Co. Kerry, V93 PY80 +353 64 663 9300
Cork - The Kingsley, Victoria Cross, Cork, T12 P680 +353 21 480 0500
Waterford - Faithlegg Hotel, Faithlegg, Co.Waterford +353 51 382000