A 3wheeler is no hihgway tool and all other streets will restrict you to lower average speeds than a 1000 mile day drive would require.
When I was younger I did Bucharest/Vienna several times within a day. 1250km (less than 1000miles!) and only 100km of highway that time. Drove a 3liter BMW and needed 13 to 16 hours at speeds far above legal speed limits...
I would not recommend to do that distance in a M3W.
And I wonder if a Mog3W would survive 16 hours at an average speed of 60miles/hour
