my '22 CX has been around the alps/dolomites very year since I got it. on both standard suspension & nitrons. two chunky 100kg passengers & two 10-12kg duffel bags on the rack plus the rear shelf stuffed with water bottles , cameras etc. I take all the back roads including single track. there can be lots of road works on the passes too, with rough unpaved sections ......never grounded yet!
they do stick me on the single deck euro shuttle tho' (car identified as a low vehicle). in town, I just do the usual speed hump management.
ive also got lots of tips on routes if its the first time you've done it .. you're not too far away.